Clinical Immunology

CLIP correct answer: Remnant of Ii (invariant chain) MIIC Compartments correct answer: Peptide loading compartments for MHC class II Viruses that target MHC antigen processing pathways correct answer: Long-life viruses eg herpes, cytomegalovirus (pulls MHC from ER membrane into cytosol to degrade it) and HIV (enters CD4 cells and destroys them -> body must target own CD4 cells to eliminate it -> HIV can become quiescent and integrate DNA into host DNA to form a provirus) Caspas...

Grafts exchanged between identical twins or animals that are identical to one another are known as... A) Alloreactive B) Allogeneic C) Syngeneic D)Xenogeneic correct answer: C) Syngeneic Grafts from one person to another are known as... A) Alloreactive B) Allogeneic C) Syngeneic D)Xenogeneic correct answer: B) Allogeneic Grafts from one species to another are known as... A) Alloreactive B) Allogeneic C) Syngeneic D)Xenogeneic correct answer: D)Xenogeneic What serv...

If a person shows production of interferons in his body, the chances are that he has got an infection: a. tanatus b. malaria c. typhoid d. measles correct answer: d. measles The blood group, with antibody A and antibody B is: a. O b. A c. B d. AB correct answer: a. O Antibodies in our body are complex ________? correct answer: glycoproteins HIV that causes AIDS, first starts destroying ________? correct answer: helper T lymphocytes The interferons are _____? correct answe...

1) Which of the following is characteristic of antibodies? A) carbohydrate structure B) composed of heavy and light polypeptide chains C) three binding sites per antibody monomer D) incapable of being transferred from one person to another correct answer: B) composed of heavy and light polypeptide chains 2) Which of the following is associated with passive immunity? A) long-term immune protection B) infusion of weakened viruses C) passage of IgG antibodies from a pregnant mothe...

Which integrin mediates firm adhesion? a. ICAM-1 b. sialyl-Lewis^x c. LFA-1 d. VCAM-1 correct answer: C. LFA-1 Chemotaxis refers to what? a. the hemodynamic changes that take place within an inflamed area b. expression of CAMS on the surfaces of monocytes/macrophages c. the directional migration of cells in response to a chemical concentration gradient d. the release of cytokines as a response to antigen binding correct answer: c. the directional migration of cells in response to a ...

A codon consists of a sequence of how many nucleotides? a. one b. two c. three d. four correct answer: c What amino acid is used to initiate most proteins in eukaryotes? a. methionine b. alanine c. proline d. arginine correct answer: a The process of protein synthesis is also called: a. translocation b. transcription c. translation d. transduction e. transformation correct answer: c Protein structure characterized by the combination of different proteins ...

Lifestyle counseling for taking oral corticosteroid for 3 months or longer correct answer: Only "A" level of evidence: Calcium intake 1200-1500 mg/d AND Vitamin D supplementation 800U-1000U If oral steroids are longer than 3 montns correct answer: a pharmacologic agent for glucocorticoid induced osteoporosis should be added. START when oral corticosteroid starts. Consider: postmenopausal status or age greater than 50 for men, dose of steroid, fracture risk (FRAX tool) FRAX correct answ...